Gene mutations can be classified in two major ways: Mutations range in size they can affect anywhere from a single DNA building block (base pair) to a large segment of a chromosome that includes multiple genes. Let’s begin with a question: What is a gene mutation and how do mutations occur?Ī gene mutation is a permanent alteration in the DNA sequence that makes up a gene, such that the sequence differs from what is found in most people. An illustration to show an example of a DNA mutation. Image credit: Genome Research Limited Mutations in Somatic Cells and in Gametes
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